Ingredient intelligence

PDRN

Supports skin recovery, firmness and renewed radiance.

Primary concern: Wrinkles
Category: Anti Aging
Routine use: AM / PM

Ingredient intelligence

Meet the ingredient

PDRN, short for polydeoxyribonucleotide, consists of purified DNA fragments traditionally derived from salmon or trout.

Originally investigated in regenerative applications, PDRN has become a prominent Korean skincare ingredient. In topical formulas, it is used to support the appearance of skin recovery, elasticity and overall vitality.

Why TOTOKA selects it

PDRN represents the innovation-led side of Korean skincare. Rather than focusing on a single visible concern, it is used to support skin that appears tired, stressed or less resilient.

Its recovery-focused profile makes it especially attractive for mature, dehydrated or compromised-looking skin.

INGREDIENT SNAPSHOT

What it brings to your skin

The essential information, without the ingredient overload.

PDRN helps support the skin’s natural renewal and recovery processes. In cosmetic formulas, it can contribute to a smoother, firmer and more revitalised appearance while helping stressed skin feel more comfortable.

Its conditioning and recovery-supporting properties may also improve hydration, barrier resilience and overall radiance.

Targeted support
A focused benefit for a balanced, results-oriented routine.
Skin compatibility
Designed to integrate naturally into intelligent skincare layering.
Routine versatility
Works across simple and advanced Korean skincare routines.

Ingredient pairings

Works beautifully with

Hyaluronic Acid

Ingredient profile A hydration-focused ingredient that helps attract and hold moisture, leaving the skin looking plumper, smoother and more refreshed. Explore ingredient

Niacinamide

Ingredient profile A brightening and barrier-supporting ingredient that helps balance the look of uneven tone, pores and excess oil. Explore ingredient

Adenosine

Ingredient profile Anti Aging Explore ingredient

Routine placement

Where it fits

Apply PDRN products after cleansing and toning, before moisturiser. It can generally be used morning and evening in serums, ampoules, masks and creams.

Follow the directions of the individual formula and complete your morning routine with broad-spectrum sunscreen.